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Gurriel was dealing with left wrist soreness and available off the bench but did not play as the Blue Jays took the series opener 4-0 at PNC Park Friday night.
The native of Sancti Spiritus, Cuba, is slashing .290/.341/.397 with five home runs and 51 RBI this season.
Right-hander Trevor Richards will take the mound for the Blue Jays while the Pirates will send righty Johan Ovideo.
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